2017

Publikationen des Jahres 2017

Barmeyer, C., M. Schumann, T. Meyer, C. Zielinski, T. Zuberbier, B. Siegmund, J.D. Schulzke, S. Daum, and R. Ullrich (2017).

Long-term response to gluten-free diet as evidence for non-celiac wheat sensitivity in one third of patients with diarrhea-dominant and mixed-type irritable bowel syndrome.

Int J Colorectal Dis. 32:29-39.

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Belova, V., P. Beyer, E. Meister, T. Linderl, M.U. Halbich, M. Gerhard, S. Schmidt, T. Zechel, T. Meisel, A.V. Generalov, A.S. Anselmo, R. Scholz, O. Konovalov, A. Gerlach, M. Koch, A. Hinderhofer, A. Opitz, W. Brutting, and F. Schreiber (2017).

Evidence for Anisotropic Electronic Coupling of Charge Transfer States in Weakly Interacting Organic Semiconductor Mixtures.

J Am Chem Soc. 139:8474-8486.

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Bowl, M.R., M.M. Simon, N.J. Ingham, S. Greenaway, L. Santos, H. Cater, S. Taylor, J. Mason, N. Kurbatova, S. Pearson, L.R. Bower, D.A. Clary, H. Meziane, P. Reilly, O. Minowa, L. Kelsey, C. International Mouse Phenotyping, G.P. Tocchini-Valentini, X. Gao, A. Bradley, W.C. Skarnes, M. Moore, A.L. Beaudet, M.J. Justice, J. Seavitt, M.E. Dickinson, W. Wurst, M.H. de Angelis, Y. Herault, S. Wakana, L.M.J. Nutter, A.M. Flenniken, C. McKerlie, S.A. Murray, K.L. Svenson, R.E. Braun, D.B. West, K.C.K. Lloyd, D.J. Adams, J. White, N. Karp, P. Flicek, D. Smedley, T.F. Meehan, H.E. Parkinson, L.M. Teboul, S. Wells, K.P. Steel, A.M. Mallon, and S.D.M. Brown (2017).

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

Nat Commun. 8:886.

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Bhattacharjee, S., N. Kalbfuss, and C. Prazeres da Costa (2017).

Parasites, microbiota and metabolic disease.

Parasite immunology. 39(5).

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Cho, Y.L., M. Flossdorf, L. Kretschmer, T. Hofer, D.H. Busch, and V.R. Buchholz (2017).

TCR Signal Quality Modulates Fate Decisions of Single CD4+ T Cells in a Probabilistic Manner.

Cell Rep. 20:806-818.

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Cossarizza A, Chang HD, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J. (2017).

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Eur J Immunol. 47:1584-1797.

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Egana, I., H. Kaito, A. Nitzsche, L. Becker, C. Ballester-Lopez, C. Niaudet, M. Petkova, W. Liu, M. Vanlandewijck, A. Vernaleken, T. Klopstock, H. Fuchs, V. Gailus-Durner, M. Hrabe de Angelis, H. Rask-Andersen, H.J. Johansson, J. Lehtio, L. He, A.O. Yildirim, M. Hellstrom, and C. German Mouse Clinic (2017).

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema.

Sci Rep. 7:15453.

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Filomena, A., A. Guenther, H. Planatscher, F. Topin, J. She, L. Formichella, L. Terradot, M. Gerhard, T.O. Joos, H. Meyer, and N. Schneiderhan-Marra (2017).

Performance of a Multiplex Serological Helicobacter pylori Assay on a Novel Microfluidic Assay Platform.

Proteomes. 5(4).

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Foreman, S.C., B.J. Schwaiger, J. Gempt, P.M. Jungmann, V. Kehl, C. Delbridge, N. Wantia, C. Zimmer, and J.S. Kirschke (2017).

MR and CT Imaging to Optimize CT-Guided Biopsies in Suspected Spondylodiscitis.

World Neurosurg. 99:726-734 e727.

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Formichella, L., L. Romberg, H. Meyer, C. Bolz, M. Vieth, M. Geppert, G. Gottner, C. Nolting, W. Schepp, A. Schneider, K. Ulm, P. Wolf, I.L. Holster, E.J. Kuipers, B. Birkner, E. Soutschek, and M. Gerhard (2017).

Validation of a Novel Immunoline Assay for Patient Stratification according to Virulence of the Infecting Helicobacter pylori Strain and Eradication Status.

J Immunol Res. 2017:8394593.

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Fuchs, H., J.A. Aguilar-Pimentel, O.V. Amarie, L. Becker, J. Calzada-Wack, Y.L. Cho, L. Garrett, S.M. Holter, M. Irmler, M. Kistler, M. Kraiger, P. Mayer-Kuckuk, K. Moreth, B. Rathkolb, J. Rozman, P. da Silva Buttkus, I. Treise, A. Zimprich, K. Gampe, C. Hutterer, S. Leuchtenberger, H. Maier, M. Miller, A. Scheideler, M. Wu, J. Beckers, R. Bekeredjian, M. Brielmeier, D.H. Busch, M. Klingenspor, T. Klopstock, M. Ollert, C. Schmidt-Weber, T. Stoeger, E. Wolf, W. Wurst, A.O. Yildirim, A. Zimmer, V. Gailus-Durner, and M. Hrabe de Angelis (2017).

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Behav Brain Res.pii: S0166-4328(17)30931-2.

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Keib, A., P.S. Gunther, B. Faist, A. Halenius, D.H. Busch, M. Neuenhahn, G. Jahn, and K.M. Dennehy (2017).

Presentation of a Conserved Adenoviral Epitope on HLA-C*0702 Allows Evasion of Natural Killer but Not T Cell Responses.

Viral Immunol. 30:149-156.

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Kirschner, A., M. Thiede, T.G. Grunewald, R. Alba Rubio, G.H. Richter, T. Kirchner, D.H. Busch, S. Burdach, and U. Thiel (2017).

Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo.

Oncoimmunology. 6:e1273301.

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Klar, K., S. Perchermeier, S. Bhattacharjee, H. Harb, T. Adler, R. Istvanffy, E. Loffredo-Verde, R.A.O. R, H. Renz, and C. Prazeres da Costa (2017).

Chronic schistosomiasis during pregnancy epigenetically reprograms T-cell differentiation in offspring of infected mothers.

Eur J Immunol. 47:841-847.

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Li, Z.X., L.L. Huang, C. Liu, L. Formichella, Y. Zhang, Y.M. Wang, L. Zhang, J.L. Ma, W.D. Liu, K. Ulm, J.X. Wang, L. Zhang, M. Bajbouj, M. Li, M. Vieth, M. Quante, T. Zhou, L.H. Wang, S. Suchanek, E. Soutschek, R. Schmid, M. Classen, W.C. You, M. Gerhard, and K.F. Pan (2017).

Cut-off optimization for (13)C-urea breath test in a community-based trial by mathematic, histology and serology approach.

Sci Rep. 7:2072.

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Manfrini, N., S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M.H. de Angelis, and S. Biffo (2017).

Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation.

Data Brief. 14:653-658.

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Manfrini, N., S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, D. Brina, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M. Hrabe de Angelis, and S. Biffo (2017).

High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.

Dev Comp Immunol. 77:69-76.

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Mejias-Luque, R., J. Zoller, F. Anderl, E. Loew-Gil, M. Vieth, T. Adler, D.B. Engler, S. Urban, J.L. Browning, A. Muller, M. Gerhard, and M. Heikenwalder (2017).

Lymphotoxin beta receptor signalling executes Helicobacter pylori-driven gastric inflammation in a T4SS-dependent manner.

Gut. 66:1369-1381.

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Mejias-Luque, R., and M. Gerhard (2017).

Immune Evasion Strategies and Persistence of Helicobacter pylori.

Curr Top Microbiol Immunol. 400:53-71.

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Mohr, F., J.C. Fischer, M. Nikolaus, C. Stemberger, S. Dreher, A. Verschoor, T. Haas, H. Poeck, and D.H. Busch (2017).

Minimally manipulated murine regulatory T cells purified by reversible Fab Multimers are potent suppressors for adoptive T-cell therapy.

Eur J Immunol. 47:2153-2162.

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Neuenhahn, M., J. Albrecht, M. Odendahl, F. Schlott, G. Dossinger, M. Schiemann, S. Lakshmipathi, K. Martin, D. Bunjes, S. Harsdorf, E.M. Weissinger, H. Menzel, M. Verbeek, L. Uharek, N. Kroger, E. Wagner, G. Kobbe, T. Schroeder, M. Schmitt, G. Held, W. Herr, L. Germeroth, H. Bonig, T. Tonn, H. Einsele, D.H. Busch, and G.U. Grigoleit (2017).

Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT.

Leukemia. 31:2161-2171.

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Pascual-Reguant, A., J. Bayat Sarmadi, C. Baumann, R. Noster, D. Cirera-Salinas, C. Curato, P. Pelczar, S. Huber, C.E. Zielinski, M. Lohning, A.E. Hauser, and E. Esplugues (2017).

TH17 cells express ST2 and are controlled by the alarmin IL-33 in the small intestine.

Mucosal Immunol. 10:1431-1442.

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Poltorak, M.P., and C.E. Zielinski (2017).

Hierarchical governance of cytokine production by 6-sulfo LacNAc (slan) dendritic cells for the control of psoriasis pathogenesis.

Exp Dermatol. 26:317-318.

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Schlott, F., D. Steubl, D. Hoffmann, E. Matevossian, J. Lutz, U. Heemann, V. Hosel, D.H. Busch, L. Renders, and M. Neuenhahn (2017).

Primary Cytomegalovirus Infection in Seronegative Kidney Transplant Patients Is Associated with Protracted Cold Ischemic Time of Seropositive Donor Organs.

PLoS One. 12:e0171035.

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Schmidt, M.O., K.A. Garman, Y.G. Lee, C. Zuo, P.J. Beck, M. Tan, J.A. Aguilar-Pimentel, M. Ollert, C. Schmidt-Weber, H. Fuchs, V. Gailus-Durner, M. Hrabe de Angelis, C. German Mouse Clinic, E. Tassi, A.T. Riegel, and A. Wellstein (2018).

The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.

J Invest Dermatol. 138:179-188.

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Schreck, C., R. Istvanffy, C. Ziegenhain, T. Sippenauer, F. Ruf, L. Henkel, F. Gartner, B. Vieth, M.C. Florian, N. Mende, A. Taubenberger, A. Prendergast, A. Wagner, C. Pagel, S. Grziwok, K.S. Gotze, J. Guck, D.C. Dean, S. Massberg, M. Essers, C. Waskow, H. Geiger, M. Schiemann, C. Peschel, W. Enard, and R.A. Oostendorp (2017).

Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells.

J Exp Med. 214:165-181.

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Textor, A., K. Schmidt, P.M. Kloetzel, B. Weissbrich, C. Perez, J. Charo, K. Anders, J. Sidney, A. Sette, T.N. Schumacher, C. Keller, D.H. Busch, U. Seifert, and T. Blankenstein (2017).

Correction: Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

J Exp Med. 214:567.

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Thiel, U., S.J. Schober, I. Einspieler, A. Kirschner, M. Thiede, D. Schirmer, K. Gall, F. Blaeschke, O. Schmidt, S. Jabar, A. Ranft, R. Alba Rubio, U. Dirksen, T.G.P. Grunewald, P.H. Sorensen, G.H.S. Richter, I.T. von Luttichau, D.H. Busch, and S.E.G. Burdach (2017).

Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells.

Oncoimmunology. 6:e1312239.

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Trsan, T., K. Vukovic, P. Filipovic, A.L. Brizic, N.A.W. Lemmermann, K. Schober, D.H. Busch, W.J. Britt, M. Messerle, A. Krmpotic, and S. Jonjic (2017).

Cytomegalovirus vector expressing RAE-1gamma induces enhanced anti-tumor capacity of murine CD8(+) T cells.

Eur J Immunol. 47:1354-1367.

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Tunger, A., R. Wehner, M. von Bonin, D. Kuhn, F. Heidenreich, S. Matko, M. Nauerth, E. Rucker-Braun, S. Dietz, C.S. Link, A. Eugster, M. Odendahl, D.H. Busch, T. Tonn, E. Bonifacio, L. Germeroth, J. Schetelig, M.P. Bachmann, M. Bornhauser, and M. Schmitz (2017).

Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology.

Leuk Lymphoma. 58:1246-1249.

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Wisskirchen, K., K. Metzger, S. Schreiber, T. Asen, L. Weigand, C. Dargel, K. Witter, E. Kieback, M.F. Sprinzl, W. Uckert, M. Schiemann, D.H. Busch, A.M. Krackhardt, and U. Protzer (2017).

Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use.

PLoS One. 12:e0182936.

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Wustner, S., F. Anderl, A. Wanisch, C. Sachs, K. Steiger, A. Nerlich, M. Vieth, R. Mejias-Luque, and M. Gerhard (2017).

Helicobacter pylori gamma-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence.

Sci Rep. 7:13636.

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Xie, K., F. Neff, A. Markert, J. Rozman, J.A. Aguilar-Pimentel, O.V. Amarie, L. Becker, R. Brommage, L. Garrett, K.S. Henzel, S.M. Holter, D. Janik, I. Lehmann, K. Moreth, B.L. Pearson, I. Racz, B. Rathkolb, D.P. Ryan, S. Schroder, I. Treise, R. Bekeredjian, D.H. Busch, J. Graw, G. Ehninger, M. Klingenspor, T. Klopstock, M. Ollert, M. Sandholzer, C. Schmidt-Weber, M. Weiergraber, E. Wolf, W. Wurst, A. Zimmer, V. Gailus-Durner, H. Fuchs, M. Hrabe de Angelis, and D. Ehninger (2017).

Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Nat Commun. 8:155.

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Zielinski, C.E (2017).

Human T cell immune surveillance: Phenotypic, functional and migratory heterogeneity for tailored immune responses.

Immunol Lett. 190:125-129.

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