Aktuelle Publikationen

Publikationen des Jahres 2020

Afridi, S.Q., H. Moeini, B. Kalali, J.M. Wettengel, O. Quitt, R. Semper, M. Gerhard, U. Protzer, and D. Hoffmann. 2020.

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.

Braz J Microbiol. 51:183-187.


Aguilar-Pimentel, J.A., Y.L. Cho, R. Gerlini, J. Calzada-Wack, M. Wimmer, P. Mayer-Kuckuk, T. Adler, C.B. Schmidt-Weber, D.H. Busch, H. Fuchs, V. Gailus-Durner, M. Ollert, M. Hrabe de Angelis, C. Ohlsson, M. Poutanen, R. Teperino, and L. Strauss. 2020.

Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice.

Sci Rep. 10:18334.


Andra, I., H. Ulrich, S. Durr, D. Soll, L. Henkel, C. Angerpointner, J. Ritter,  S. Przibilla, H. Stadler, M. Effenberger, D.H. Busch, and M. Schiemann. 2020.

An Evaluation of T-Cell Functionality After Flow Cytometry Sorting Revealed p38 MAPK Activation.

Cytometry A. 97:171-183.


Bajic, D., A. Niemann, A.K. Hillmer, R. Mejias-Luque, S. Bluemel, M. Docampo, M.C. Funk, E. Tonin, M. Boutros, B. Schnabl, D.H. Busch, T. Miki, R.M. Schmid, M.R.M. van den Brink, M. Gerhard, and C.K. Stein-Thoeringer. 2020.

Gut microbiota derived propionate regulates the expression of Reg3 mucosal lectins and ameliorates experimental colitis in mice.

J Crohns Colitis.


Barnowski, C., G. Ciupka, R. Tao, L. Jin, D.H. Busch, S. Tao, and I. Drexler. 2020.

Efficient Induction of Cytotoxic T Cells by Viral Vector Vaccination Requires STING-Dependent DC Functions.

Front Immunol. 11:1458.


Berkefeld, A., F.K. Berger, B.C. Gartner, N. Wantia, A. Prinzing, K.L. Laugwitz, D.H. Busch, and K. Rothe. 2020.

Clostridioides (Clostridium) difficile Pacemaker Infection.

Open Forum Infect Dis. 7:ofaa487.


D'Ippolito, E., K.I. Wagner, and D.H. Busch. 2020.

Needle in a Haystack: The Naive Repertoire as a Source of T Cell Receptors for AdoptiveTherapy with Engineered T Cells.

Int J Mol Sci. 21.


de Los Reyes Jimenez, M., A. Lechner, F. Alessandrini, S. Bohnacker, S. Schindela, A. Trompette, P. Haimerl, D. Thomas, F. Henkel, A. Mourao, A. Geerlof, C.P. da Costa, A.M. Chaker, B. Brune, R. Nusing, P.J. Jakobsson, W.A. Nockher, M.J. Feige, M. Haslbeck, C. Ohnmacht, B.J. Marsland, D. Voehringer, N.L. Harris, C.B. Schmidt-Weber, and J. Esser-von Bieren. 2020.

An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products.

Sci Transl Med. 12.


Grassmann, S., L. Mihatsch, J. Mir, A. Kazeroonian, R. Rahimi, S. Flommersfeld, K. Schober, I. Hensel, J. Leube, L.O. Pachmayr, L. Kretschmer, Q. Zhang, A. Jolly, M.Z. Chaudhry, M. Schiemann, L. Cicin-Sain, T. Hofer, D.H. Busch, M. Flossdorf, and V.R. Buchholz. 2020.

Early emergence of T central memory precursors programs clonal dominance during chronic viral infection.

Nat Immunol. 21:1563-1573.


Hamway, Y., K. Taxauer, K. Moonens, V. Neumeyer, W. Fischer, V. Schmitt, B.B. Singer, H. Remaut, M. Gerhard, and R. Mejias-Luque. 2020.

Cysteine Residues in Helicobacter pylori Adhesin HopQ are Required for CEACAM-HopQ Interaction and Subsequent CagA Translocation.

Microorganisms. 8.


Kollmus, H., H. Fuchs, C. Lengger, H. Haselimashhadi, M.A. Bogue, M.A. Ostereicher, M. Horsch, T. Adler, J.A. Aguilar-Pimentel, O.V. Amarie,  L. Becker, J. Beckers, J. Calzada-Wack, L. Garrett, W. Hans, S.M. Holter, T. Klein-Rodewald, H. Maier, P. Mayer-Kuckuk, G. Miller, K. Moreth, F. Neff, B. Rathkolb, I. Racz, J. Rozman, N. Spielmann, I. Treise, D. Busch, J. Graw, T. Klopstock, E. Wolf, W. Wurst, A.O. Yildirim, J. Mason, A. Torres,  T. Mouse Phenome Database, R. Balling, T. Mehaan, V. Gailus-Durner, K. Schughart, and M. Hrabe de Angelis. 2020.

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.

Mamm Genome. 31:30-48.


Kretschmer, L., M. Flossdorf, J. Mir, Y.L. Cho, M. Plambeck, I. Treise, A. Toska, S. Heinzel, M. Schiemann, D.H. Busch, and V.R. Buchholz. 2020.

Differential expansion of T central memory precursor and effector subsets is regulated by division speed.

Nat Commun. 11:113.


Kuhne, J.F., C. Neudorfl, K. Beushausen, J. Keil, S. Malysheva, F. Wandrer, H. Haller, M. Messerle, C. Blume, M. Neuenhahn, F. Schlott, W. Hammerschmidt, R. Zeidler, and C.S. Falk. 2020.

Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors.

Transpl Immunol:101291.


Loffredo-Verde, E., S. Bhattacharjee, A. Malo, J. Festag, A.D. Kosinska, M. Ringelhan, S. Rim Sarkar, K. Steiger, M. Heikenwaelder, U. Protzer, and C.U. Prazeres da Costa. 2020.

Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection.

J Infect Dis. 221:1448-1461.


Lucienne, M., J.A. Aguilar-Pimentel, O.V. Amarie, L. Becker, J. Calzada-Wack, P. da Silva-Buttkus, L. Garrett, S.M. Holter, P. Mayer-Kuckuk, B. Rathkolb, J. Rozman, N. Spielmann, I. Treise, D.H. Busch, T. Klopstock, C. Schmidt-Weber, E. Wolf, W. Wurst, M. Forny,  D. Mathis, R. Fingerhut, D.S. Froese, V. Gailus-Durner, H. Fuchs, M.H. de Angelis, and M.R. Baumgartner. 2020.

In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.

Biochim Biophys Acta Mol Basis Dis. 1866:165622.


Muller, T.R., C. Schuler, M. Hammel, A. Kohler, S. Jutz, J. Leitner, K. Schober, D.H. Busch, and P. Steinberger. 2020.

A T-cell reporter platform for high-throughput and reliable investigation of TCR function and biology.

Clin Transl Immunology. 9:e1216.


Poltorak, M.P., P. Graef, C. Tschulik, M. Wagner, V. Cletiu, S. Dreher, B. Borjan, S.P. Fraessle, M. Effenberger, M. Turk, D.H. Busch, J. Plitzko, D.G. Kugler, S. Ragan, T. Schmidt, C. Stemberger, and L. Germeroth. 2020.

Expamers: a new technology to control T cell activation.

Sci Rep. 10:17832.


Prodjinotho, U.F., J. Lema, M. Lacorcia, V. Schmidt, N. Vejzagic, C. Sikasunge, B. Ngowi, A.S. Winkler, and C. Prazeres da Costa. 2020.

Host immune responses during Taenia solium Neurocysticercosis infection and treatment.

PLoS Negl Trop Dis. 14:e0008005.


Rothe, K., S. Feihl, J. Schneider, F. Wallnofer, M. Wurst, M. Lukas, M. Treiber, T. Lahmer, M. Heim, M. Dommasch, B. Waschulzik, A. Zink, C. Querbach, D.H. Busch, R.M. Schmid, G. Schneider, and C.D. Spinner. 2020.

Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship.

Eur J Clin Microbiol Infect Dis.


Rothe, K., J. Katchanov, J. Schneider, C.D. Spinner, V. Phillip, D.H. Busch,  D. Tappe, R. Braren, R.M. Schmid, and J. Slotta-Huspenina. 2020.

Strongyloides stercoralis hyperinfection syndrome presenting as mechanical ileus after short-course oral steroids for chronic obstructive pulmonary disease (COPD) exacerbation.

Parasitol Int. 76:102087.


Rothe, K., S. Rasch, N. Wantia, A. Poszler, J. Ulrich, C. Schlag, W. Huber, R.M. Schmid, D.H. Busch, and T. Lahmer. 2020.

Aspergillus fumigatus cholangitis in a patient with cholangiocarcinoma: case report and review of the literature.



Rothe, K., C.D. Spinner, B. Waschulzik, C. Janke, J. Schneider, H. Schneider, K. Braitsch, C. Smith, R.M. Schmid, D.H. Busch, and J. Katchanov. 2020.

A diagnostic algorithm for detection of urinary tract infections in hospitalized patients with bacteriuria: The "Triple F" approach supported by Procalcitonin and paired blood and urine cultures.

PLoS One. 15:e0240981.


Schober, K., P. Fuchs, J. Mir, M. Hammel, L. Fanchi, M. Flossdorf, and D.H. Busch. 2020.

The CMV-Specific CD8(+) T Cell Response Is Dominated by Supra-Public Clonotypes with High Generation Probabilities.

Pathogens. 9.


Schober, K., T.R. Muller, and D.H. Busch. 2020.

Orthotopic T-Cell Receptor Replacement-An "Enabler" for TCR-Based Therapies.

Cells. 9.


Schober, K., M. Sambucci, G.E. Patzer, and F. Laudisi. 2020.

Young immunologists of Europe, unite!

Eur J Immunol. 50:480-483.


Schober, K., F. Voit, S. Grassmann, T.R. Muller, J. Eggert, S. Jarosch, B. Weissbrich, P. Hoffmann, L. Borkner, E. Nio, L. Fanchi, C.R. Clouser, A. Radhakrishnan, L. Mihatsch, P. Luckemeier, J. Leube, G. Dossinger, L. Klein, M. Neuenhahn, J.D. Oduro, L. Cicin-Sain, V.R. Buchholz, and D.H. Busch. 2020.

Reverse TCR repertoire evolution toward dominant  low-affinity clones during chronic CMV infection.

Nat Immunol. 21:434-441.


Schuierer, L., M. Gebhard, H.G. Ruf, U. Jaschinski, T.M. Berghaus, M. Wittmann, G. Braun, D.H. Busch, and R. Hoffmann. 2020.

Impact of acyclovir use on survival of patients with ventilator-associated  pneumonia and high load herpes simplex virus replication.

Crit Care. 24:12.


Softley, C.A., K.M. Zak, M.J. Bostock, R. Fino, R.X. Zhou, M. Kolonko, R. Mejdi-Nitiu, H. Meyer, M. Sattler, and G.M. Popowicz. 2020.

Structure and molecular recognition mechanism of IMP-13 metallo-beta-lactamase. 

Antimicrob Agents Chemother.


Stenger, D., T.A. Stief, T. Kaeuferle, S. Willier, F. Rataj, K. Schober, B. Vick,  R. Lotfi, B. Wagner, T.G.P. Grunewald, S. Kobold, D.H. Busch, I. Jeremias,  F. Blaeschke, and T. Feuchtinger. 2020.

Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.

Blood. 136:1407-1418.