Publikationen 2014

Publikationen des Jahres 2014

Albert, M.H., Mannert, J., Fleischmann, K.K., Schiemann, M., Pagel, P., Schmid, I., and Magg, T. 2014.

MiRNome and transcriptome aided pathway analysis in human regulatory T cells.

Genes and immunity15(5): 303-312. doi: 10.1038/gene.2014.20.

mehr...


Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, Chen Y, Zhao X, Schmidl C, Suzuki T, Ntini E, Arner E, Valen E, Li K, Schwarzfischer L, Glatz D, Raithel J, Lilje B, Rapin N, Bagger FO, Jorgensen M, Andersen PR, Bertin N, Rackham O, Burroughs AM, Baillie JK, Ishizu Y, Shimizu Y, Furuhata E, Maeda S, Negishi Y, Mungall CJ, Meehan TF, Lassmann T, Itoh M, Kawaji H, Kondo N, Kawai J, Lennartsson A, Daub CO, Heutink P, Hume DA, Jensen TH, Suzuki H, Hayashizaki Y, Muller F, Consortium F, Forrest AR, Carninci P, Rehli M and Sandelin A

Collaborators: Forrest AR, Kawaji H, Rehli M, Baillie JK, de Hoon MJ, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M, Andersson R, Mungall CJ, Meehan TF, Schmeier S, Bertin N, Jørgensen M, Dimont E, Arner E, Schmid C, Schaefer U, Medvedeva YA, Plessy C, Vitezic M, Severin J, Semple CA, Ishizu Y, Young RS, Francescatto M, Alam I, Albanese D, Altschuler GM, Arakawa T, Archer JA, Arner P, Babina M, Rennie S, Balwierz PJ, Beckhouse AG, Pradhan-Bhatt S, Blake JA, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Burroughs AM, Califano A, Cannistracti CV, Carbajo D, Chen Y, Chierici M, Ciani Y, Clevers HC, Dalla E, Davis CA, Detmar M, Diehl AD, Dohi T, Drabløs F, Edge AS, Edinger M, Ekwall K, Endoh M, Enomoto H, Fagiolini M, Fairbairn L, Fang H, Farach-Carson MC, Faulkner GJ, Favorov AV, Fisher ME, Frith MC, Fujita R, Fukuda S, Furlanello C, Furuno M, Furusawa J, Geijtenbeek TB, Gibson AP, Gingeras T, Goldowitz D, Gough J, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Harbers M, Harshbarger J, Hasegawa A, Hasegawa Y, Hashimoto T, Herlyn M, Hitchens KJ, Ho Sui SJ, Hofman OM, Hoof I, Hori F, Huminiecki L, Iida K, Ikawa T, Jankovic BR, Jia H, Joshi A, Jurman G, Kaczkowski B, Kai C, Kaida K, Kaiho A, Kajiyama K, Kanamori-Katayama M, Kasianov AS, Kasukawa T, Katayama S, Kato S, Kawaguchi S, Kawamoto H, Kawamura YI, Kawashima T, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klinken SP, Knox AJ, Kojima M, Kojima S, Kondo N, Koseki H, Koyasu S, Krampitz S, Kubosaki A, Kwon AT, Laros JF, Lee W, Lennartsson A, Li K, Lilje B, Lipovich L, Mackay-Sim A, Manabe R, Mar JC, Marchand B, Mathelier A, Mejhert N, Meynert A, Mizuno Y, de Lima Morais DA, Morikawa H, Morimoto M, Moro K, Motakis E, Motohashi H, Mummery CL, Murata M, Nagao-Sato S, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nakazato K, van Nimwegen E, Ninomiya N, Nishiyori H, Noma S, Nozaki T, Ogishima S, Ohkura N, Ohmiya H, Ohno H, Onshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Pain A, Passier R, Patrikakis M, Persson H, Piazza S, Prendergast JG, Rackham OJ, Ramilowski JA, Rashid M, Ravasi T, Rizzu P, Roncador M, Roy S, Rye MB, Saijyo E, Sajantila A, Saka A, Sakaguchi S, Sakai M, Sato H, Satoh H, Savvi S, Saxena A, Schneider C, Schultes EA, Schultz-Tanzil GG, Schwegmann A, Sengstag T, Sheng G, Shimoji H, Shimoni Y, Shin JW, Simon C, Sugiyama D, Sugiyama T, Suzuki M, Suzuki N, Swoboda RK, 't Hoen PA, Tagami M, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tatum Z, Thompson M, Toyoda H, Toyodo T, Valen E, van de Wetering M, van den Berg LM, Verardo R, Vijayan D, Vorontsov IE, Wasserman WW, Watanabe S, Wells CA, Winteringham LN, Wolvetang E, Wood EJ, Yamaguchi Y, Yamamoto M, Yoneda M, Yonekura Y, Yoshida S, Zabierowski SE, Zhang PG, Zhao X, Zucchelli S, Summers KM, Suzuki H, Daub CO, Kawai J, Heutink P, Hide W, Freeman TC, Lenhard B, Bajic VB, Taylor MS, Makeev VJ, Sandelin A, Hume DA, Carninci P, Hayashizaki Y.(2014)

An atlas of active enhancers across human cell types and tissues.

Nature507:455-61. doi: 10.1038/nature12787

mehr...


Beil J and Buch T (2014)

Generation of Bacterial Artificial Chromosome (BAC) Transgenic Mice.

Methods Mol Biol1194:157-69. doi: 10.1007/978-1-4939-1215-5_8

mehr...


Engler DB, Reuter S, van Wijck Y, Urban S, Kyburz A, Maxeiner J, Martin H, Yogev N, Waisman A, Gerhard M, Cover TL, Taube C and Muller A (2014)

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10.

Proc Natl Acad Sci U S A111:11810-5. doi: 10.1073/pnas.1410579111

mehr...


Graef P, Buchholz VR, Stemberger C, Flossdorf M, Henkel L, Schiemann M, Drexler I, Hofer T, Riddell SR and Busch DH (2014)

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells.

Immunity41:116-26. doi: 10.1016/j.immuni.2014.05.018

mehr...


Heinemann C, Heink S, Petermann F, Vasanthakumar A, Rothhammer V, Doorduijn E, Mitsdoerffer M, Sie C, Prazeres da Costa O, Buch T, Hemmer B, Oukka M, Kallies A and Korn T (2014)

IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.

Nat Commun5:3770. doi: 10.1038/ncomms4770

mehr...


Holzscheiter M, Layland LE, Loffredo-Verde E, Mair K, Vogelmann R, Langer R, Wagner H and Prazeres da Costa C (2014)

Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis.

Clin Exp Immunol175:246-57. doi: 10.1111/cei.12230

mehr...


Hutz K, Mejias-Luque R, Farsakova K, Ogris M, Krebs S, Anton M, Vieth M, Schuller U, Schneider MR, Blum H, Wagner E, Jung A and Gerhard M (2014)

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells.

Carcinogenesis35:942-50. doi: 10.1093/carcin/bgt410

mehr...


Kabisch R, Mejias-Luque R, Gerhard M and Prinz C (2014)

Involvement of Toll-Like Receptors on Helicobacter pylori-Induced Immunity.

PLoS One9:e104804. doi: 10.1371/journal.pone.0104804

mehr...


Kaebisch R, Mejias-Luque R, Prinz C and Gerhard M (2014)

Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10-mediated activation of STAT3.

J Immunol192:316-23. doi: 10.4049/jimmunol.1302476

mehr...


Kalali B, Mejias-Luque R, Javaheri A and Gerhard M (2014)

H. pylori virulence factors: influence on immune system and pathology.

Mediators Inflamm2014:426309. doi: 10.1155/2014/426309

mehr...


Kemter E, Rathkolb B, Becker L, Bolle I, Busch DH, Dalke C, Elvert R, Favor J, Graw J, Hans W, Ivandic B, Kalaydjiev S, Klopstock T, Racz I, Rozman J, Schrewe A, Schulz H, Zimmer A, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Wolf E and Aigner B (2014)

Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice.

J Biomed Sci21:68. doi: 10.1186/s12929-014-0068-0

mehr...


Klar R, Schober S, Rami M, Mall S, Merl J, Hauck SM, Ueffing M, Admon A, Slotta-Huspenina J, Schwaiger M, Stevanovic S, Oostendorp RA, Busch DH, Peschel C and Krackhardt AM (2014)

Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells.

Leukemia. doi: 10.1038/leu.2014.131

mehr...


Kraus P, V S, Yu HB, Xing X, Lim SL, Adler T, Pimentel JA, Becker L, Bohla A, Garrett L, Hans W, Holter SM, Janas E, Moreth K, Prehn C, Puk O, Rathkolb B, Rozman J, Adamski J, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Neff F, Ollert M, Stoeger T, Yildrim AO, Eickelberg O, Wolf E, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Lufkin T and Stanton LW (2014)

Pleiotropic functions for transcription factor zscan10.

PLoS One9:e104568. doi: 10.1371/journal.pone.0104568

mehr...


Neumann K, Castineiras-Vilarino M, Hockendorf U, Hannesschlager N, Lemeer S, Kupka D, Meyermann S, Lech M, Anders HJ, Kuster B, Busch DH, Gewies A, Naumann R, Gross O and Ruland J (2014)

Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death.

Immunity40:389-99. doi: 10.1016/j.immuni.2013.12.015

mehr...


Odendahl M, Grigoleit GU, Bonig H, Neuenhahn M, Albrecht J, Anderl F, Germeroth L, Schmitz M, Bornhauser M, Einsele H, Seifried E, Busch DH and Tonn T (2014)

Clinical-scale isolation of 'minimally manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus disease.

Cytotherapy16:1245-56. doi: 10.1016/j.jcyt.2014.05.023

mehr...


Pan KF, Formichella L, Zhang L, Zhang Y, Ma JL, Li ZX, Liu C, Wang YM, Goettner G, Ulm K, Classen M, You WC and Gerhard M (2014)

Helicobacter pylori antibody responses and evolution of precancerous gastric lesions in a Chinese population.

Int J Cancer 134:2118-25. doi: 10.1002/ijc.28560

mehr...


Prazeres da Costa O, Hoffman A, Rey JW, Mansmann U, Buch T and Tresch A (2014)

Selection of higher order regression models in the analysis of multi-factorial transcription data.

PLoS One9:e91840. doi: 10.1371/journal.pone.0091840

mehr...


Ritter M, Straubinger K, Schmidt S, Busch DH, Hagner S, Garn H, Prazeres da Costa C and Layland LE (2014)

Functional relevance of NLRP3 inflammasome-mediated IL-1beta during acute allergic airway inflammation.

Clin Exp Immunol.doi: 10.1111/cei.12400

mehr...


Rothhammer V, Muschaweckh A, Gasteiger G, Petermann F, Heink S, Busch DH, Heikenwalder M, Hemmer B, Drexler I and Korn T (2014)

alpha4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets.

Acta Neuropathol Commun2:27. doi: 10.1186/2051-5960-2-27

mehr...


Schneider J, De Waha P, Hapfelmeier A, Feihl S, Rommler F, Schlag C, Algul H, Schmid RM, Wantia N, Huber W and Weber A (2014)

Risk factors for increased antimicrobial resistance: a retrospective analysis of 309 acute cholangitis episodes.

J Antimicrob Chemother69:519-25. doi: 10.1093/jac/dkt373

mehr...


Schneider J, Weidner W, Hapfelmeier A, Wantia N, Feihl S, Schmid RM, Neu B, von Delius S, Algul H, Huber W and Weber A (2014)

The use of proton pump inhibitors and the spectrum and number of biliary pathogens in patients with acute cholangitis.

Aliment Pharmacol Ther39:1194-203. doi: 10.1111/apt.12694

mehr...


Schwartz C, Oeser K, Prazeres da Costa C, Layland LE and Voehringer D (2014)

T Cell-Derived IL-4/IL-13 Protects Mice against Fatal Schistosoma mansoni Infection Independently of Basophils.

J Immunol.doi: 10.4049/jimmunol.1401155

mehr...


Semper RP, Mejias-Luque R, Gross C, Anderl F, Muller A, Vieth M, Busch DH, Prazeres da Costa C, Ruland J, Gross O and Gerhard M (2014)

Helicobacter pylori-Induced IL-1beta Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island.

J Immunol.doi: 10.4049/jimmunol.1400362

mehr...


Sharif O, Gawish R, Warszawska JM, Martins R, Lakovits K, Hladik A, Doninger B, Brunner J, Korosec A, Schwarzenbacher RE, Berg T, Kralovics R, Colinge J, Mesteri I, Gilfillan S, Salmaggi A, Verschoor A, Colonna M and Knapp S (2014)

The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.

PLoS Pathog10:e1004167. doi: 10.1371/journal.ppat.1004167

mehr...


Sledzinska A, Fairbairn L and Buch T (2014)

Manipulation of T cell function and conditional gene targeting in T cells.

Methods Mol Biol1193:153-69. doi: 10.1007/978-1-4939-1212-4_15

mehr...


Snyder GA, Deredge D, Waldhuber A, Fresquez T, Wilkins DZ, Smith PT, Durr S, Cirl C, Jiang J, Jennings W, Luchetti T, Snyder N, Sundberg EJ, Wintrode P, Miethke T and Xiao TS (2014)

Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.

J Biol Chem289:669-79. doi: 10.1074/jbc.M113.523407

mehr...


Steger B, Milosevic S, Doessinger G, Reuther S, Liepert A, Braeu M, Schick J, Vogt V, Schuster F, Kroell T, Busch DH, Borkhardt A, Kolb HJ, Tischer J, Buhmann R and Schmetzer H (2014)

CD4(+)and CD8(+)T-cell reactions against leukemia-associated- or minor-histocompatibility-antigens in AML-patients after allogeneic SCT.

Immunobiology219:247-60. doi: 10.1016/j.imbio.2013.10.008

mehr...


Stemberger C, Graef P, Odendahl M, Albrecht J, Dossinger G, Anderl F, Buchholz VR, Gasteiger G, Schiemann M, Grigoleit GU, Schuster FR, Borkhardt A, Versluys B, Tonn T, Seifried E, Einsele H, Germeroth L, Busch DH and Neuenhahn M (2014)

Lowest numbers of primary CD8+ T cells can reconstitute protective immunity upon adoptive immunotherapy.

Blood124:628-37. doi: 10.1182/blood-2013-12-547349

mehr...


Straubinger K, Paul S, Prazeres da Costa O, Ritter M, Buch T, Busch DH, Layland LE and Prazeres da Costa CU (2014)

Maternal immune response to helminth infection during pregnancy determines offspring susceptibility to allergic airway inflammation.

J Allergy Clin Immunol.doi: 10.1016/j.jaci.2014.05.034

mehr...


Turqueti-Neves A, Otte M, Prazeres da Costa O, Hopken UE, Lipp M, Buch T and Voehringer D (2014)

B-cell-intrinsic STAT6 signaling controls germinal center formation.

Eur J Immunol44:2130-8. doi: 10.1002/eji.201344203

mehr...


Waldschmitt N, Berger E, Rath E, Sartor RB, Weigmann B, Heikenwalder M, Gerhard M, Janssen KP and Haller D (2014)

C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely regulated with chronic inflammation.

Mucosal Immunol.doi: 10.1038/mi.2014.34

mehr...


Wustner S, Mejias-Luque R, Koch MF, Rath E, Vieth M, Sieber SA, Haller D and Gerhard M (2014)

Helicobacter pylori gamma-glutamyltranspeptidase impairs T-lymphocyte function by compromising metabolic adaption through inhibition of cMyc and IRF4 expression.

Cell Microbiol.doi: 10.1111/cmi.12335

mehr...