Publikationen des Jahres 2022

Cunillera-Montcusí D., Beklioğlu M., Cañedo-Argüelles M., Jeppesen E., Ptacnik R., Amorim C.A., Arnott S.E., Berger S.A., Brucet S., Dugan H.A., Gerhard M., Horváth Z., Langenheder S., Nejstgaard J.C., Reinikainen M., Striebel M., Urrutia-Cordero P., Vad C.F., Zadereev E., Matias M. 2022

Freshwater salinisation: a research agenda for a saltier world.

Trends Ecol Evol. 2022 May;37(5):440-453. PMID: 35058082 DOI: 10.1016/j.tree.2021.12.005(link is external)

mehr(link is external)

Erber J., Kappler V., Haller B., Mijočević H., Galhoz A., Prazeres da Costa C., Gebhardt F., Graf N., Hoffmann D., Thaler M., Lorenz E., Roggendorf H., Kohlmayer F., Henkel A., Menden M.P., Ruland J., Spinner C.D., Protzer U., Knolle P., Lingor P.; SeCoMRI Study Group2. 2022

Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany.

Emerg Infect Dis. 2022 Mar;28(3):572-581. PMID: 35195515 PMCID: PMC8888242(link is external) DOI: 10.3201/eid2803.204436(link is external)

mehr...(link is external)

Hamway Y, Zimmermann K, Blommers MJJ, Sousa M, Häberli C, Kulkarni S, Skalicky S, Hackl M, Götte M, Keiser J, Prazeres da Costa C, Spangenberg T, Azzaoui K.

Modulation of Host-Parasite Interactions with Small Molecules Targeting Schistosoma mansoni microRNAs.

ACS Infect Dis. 2022 Sep 13. Epub ahead of print. PMID: 36098656. DOI: 10.1021/acsinfecdis.2c00360 (link is external)

mehr...(link is external)

Grassmann, S., Sun, J. C. & Buchholz, V. R. 2022

Retrogenic Color-Barcoding for Fate Mapping of Single Innate Lymphocytes.

Methods Mol. Biol. 2463, 117–127 (2022). PMID: 35344171 DOI: 10.1007/978-1-0716-2160-8_9 (link is external)

mehr...(link is external)

Hinsenkamp I., Köhler J.P., Flächsenhaar C., Hitkova I., Meessen S.E., Gaiser T., Wieland T., Weiss C., Röcken C., Mowat M., Quante M., Taxauer K., Mejias-Luque R., Gerhard M., Vogelmann R., Meindl-Beinker N., Ebert M., Burgermeister E. 2022

Functional antagonism between CagA and DLC1 in gastric cancer.

Cell Death Discov. 2022 Aug 13;8(1):358. PMID: 35963849 PMCID: PMC9376073(link is external) DOI: 10.1038/s41420-022-01134-x(link is external)

mehr...(link is external)

Jarosch S., Köhlen J., Wagner S., D'Ippolito E., Busch D.H. 2022

ChipCytometry for multiplexed detection of protein and mRNA markers on human FFPE tissue samples.

STAR Protoc. 2022 May 11;3(2):101374. PMID:35586313 PMCID: PMC9109191(link is external) DOI:10.1016/j.xpro.2022.101374


Kaeuferle T., Stief T.A., Canzar S., Kutlu N.N., Willier S., Stenger D., Ferrada-Ernst P., Habjan N., Peters A.E., Busch D.H., Feuchtinger T. 2022

Genome-wide off-target analyses of CRISPR/Cas9-mediated T-cell receptor engineering in primary human T cells.

Clin Transl Immunology. 2022 Jan 23;11(1):e1372. PMID: 35106156 PMCID: PMC8784854 (link is external) DOI:10.1002/cti2.1372 (link is external) . eCollection 2022.

mehr...(link is external)

Koch M.R., Gong R., Friedrich V., Engelsberger V., Kretschmer L., Wanisch A., Jarosch S., Ralser A., Lugen B., Quante M., Vieth M., Vasapolli R., Schulz C., Buchholz V.R., Mejías-Luque R.,  Gerhard M. 2022

CagA-specific gastric CD8+ tissue-resident T cells control Helicobacter pylori during the early infection phase

Gastroenterology. 2022 Dec 29, DOI: is external)

mehr...(link is external)

Koerber N., Priller A., Yazici S., Bauer T., Cheng C.C., Mijočević H., Wintersteller H., Jeske S., Vogel E., Feuerherd M., Tinnefeld K., Winter C., Ruland J., Gerhard M., Haller B., Christa C., Zelger O., Roggendorf H., Halle M., Erber J., Lingor P., Keppler O., Zehn D., Protzer U., Knolle P.A. 2022

Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents.

Nat Commun. 2022 Jan 10;13(1):153. PMID: 35013191 PMCID: PMC8748966(link is external) DOI: 10.1038/s41467-021-27649-y(link is external)

mehr...(link is external)

Kretschmer, L. & Buchholz, V. R. 2022

T cell memories of past divisions.

Nat. Immunol. (2022). PMID: 35449418 DOI: 10.1038/s41590-022-01193-3 (link is external)

mehr...(link is external)

Lacorcia M, Kugyelka R, Spechtenhauser L, Prodjinotho F, Hamway Y, Spangenberg T, Prazeres da Costa C.

Praziquantel Reduces Maternal Mortality and Offspring Morbidity by Enhancing Anti-Helminthic Immune Responses.

Front Immunol. 2022 Jun 27;13:878029. PMID: 35833137. DOI: 10.3389/fimmu.2022.878029(link is external)

mehr...(link is external)

Langa I, Padama F, Nhancupe N, Pondja A, Hlashwayo D, Gouveia L, Stelzle D, Prazeres da Costa C, Schmidt V, Winkler AS, Noormahomed EV.

The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique.

2022 PLoS Negl Trop Dis 16(7): e0010606. PMID 35834558. DOI: 10.1371/journal.pntd.0010606(link is external)

mehr...(link is external)

Leube J., Mühlbauer A., Andrä I., Biggel M., Busch D.H., Kretschmer L., Buchholz V.R. 2022

Single-cell fate mapping reveals widespread clonal ignorance of low-affinity T cells exposed to systemic infection

Eur J Immunol. 2022 Dec 2. PMID: 36458456 DOI: 10.1002/eji.202250009 (link is external)

mehr...(link is external)

Li X., Pan K., Vieth M., Gerhard M., Li W., Mejías-Luque R. 2022

JAK-STAT1 Signaling Pathway Is an Early Response to Helicobacter pylori Infection and Contributes to Immune Escape and Gastric Carcinogenesis.

Int J Mol Sci. 2022 Apr 8;23(8):4147. PMID: 35456965 PMCID: PMC9031264 (link is external) DOI: 10.3390/ijms23084147 (link is external)

mehr...(link is external)

Lückemeier P., Molter K.L., Jarosch S., Huppertz P., Purcarea A., Effenberger M.J.P., Nauerth M., D'Ippolito E., Schober K., Busch D.H. 2022

Global koff-rates of polyclonal T-cell populations merge subclonal avidities and predict functionality.

Eur J Immunol. 2022 Apr;52(4):582-596. DOI: 10.1002/eji.202149597 (link is external) . Epub 2022 Feb 13. PMID: 35099805

mehr...(link is external)

Mateyka L.M., Strobl P.M., Jarosch S. , Scheu S.J.C. , Busch D.H., D’Ippolito E. 2022

Gene Signatures of T-Cell Activation Can Serve as Predictors of Functionality for SARS-CoV-2-Specific T-Cell Receptors

Vaccines 2022, 10(10), 1617; is external)

mehr…(link is external)

Mateyka L.M., Grass V., Pichlmair A., Busch D.H., D'Ippolito E. 2022

SARS-CoV-2 CD8+ T cell killing assays using replicating viruses and transgenic antigens.

STAR Protoc. 2022 Aug 26;3(4):101699 PMID: 36152303 PMCID: PMC9411149 (link is external) DOI:10.1016/j.xpro.2022.101699 (link is external)

mehr...(link is external)

Neubert V., Sadek A., Burell T., Ralser A., Erhard M., Gerhard M., Seidel K., Kalali B. 2022

Validation and improvement of a multiplex PCR method to detect murine Helicobacter species in feces samples of mice.

Helicobacter. 2022 Jun;27(3):e12888. PMID:35363924 DOI: 10.1111/hel.12888 (link is external)

mehr...(link is external)

Paprckova D., Niederlova V., Moudra A., Drobek A., Pribikova M., Janusova S., Schober K., Neuwirth A., Michalik J., Huranova M., Horkova V., Cesnekova M., Simova M., Prochazka J., Balounova J., Busch D.H., Sedlacek R., Schwarzer M., Stepanek O. 2022

Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections

Front Immunol. 2022 Oct 6;13:1009198. PMID: 36275704 PMCID: PMC9582129 DOI: 10.3389/fimmu.2022.1009198(link is external)

mehr...(link is external)

Penkler M, Jacob CM, Müller R, Kenney M, Shane A Norris SA, Prazeres da Costa C, Richardson SS, Roseboom TJ, Hanson M.

Developmental Origins of Health and Disease, resilience and social justice in the COVID era.

J Dev Orig Health Dis. 2022 Aug;13(4):413-416. PMID: 34709151. DOI: 10.1017/S204017442100060X(link is external)

mehr...(link is external)

Plambeck M., Kazeroonian A., Loeffler D., Kretschmer L., Salinno C., Schroeder T., Busch D.H., Flossdorf M., Buchholz V.R. 2022

Heritable changes in division speed accompany the diversification of single T cell fate.

Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2116260119.PMID: 35217611  PMCID: PMC8892279 (link is external) DOI:10.1073/pnas.2116260119(link is external)

mehr...(link is external)

Prodjinotho U.F., Gres V., Henkel F., Lacorcia M., Dandl R., Haslbeck M., Schmidt V., Winkler A.S., Sikasunge C., Jakobsson P.J., Henneke P., Esser-von Bieren J., Prazeres da Costa C. 2022

Helminthic dehydrogenase drives PGE2 and IL-10 production in monocytes to potentiate Treg induction.

EMBO Rep. 2022 May 4;23(5):e54096. PMID: 35357743 PMCID: PMC9066053  (link is external)DOI:10.15252/embr.202154096 (link is external)

mehr...(link is external)

Purcarea A., Jarosch S., Barton J., Grassmann  S., Pachmayr  L., D'Ippolito  E., Hammel  M., Hochholzer  A., Wagner  K.I., van den Berg J.H., Buchholz  V.R., Haanen J.B.A.G., Busch  D.H., Schober K. 2022

Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.

Sci Immunol. 2022 Aug 12;7(74): PMID:35960818 DOI: 10.1126/sciimmunol.abm2077 (link is external)

mehr...(link is external)

Radisch S., Poltorak M.P., Wagner M., Cletiu V., Radisch C, Treise I., Pann S., Weigt A., Artner S., Dreher S., Fechner F., Borjan B., Fraessle S.P., Effenberger M., Benke E., Navratil G., Hentschel N., Busch D.H., Schmidt T., Stemberger C., Germeroth L. 2022

Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation.

Sci Rep. 2022 Apr 21;12(1):6572. PMID: 35449227  PMCID: PMC9023455 (link is external) DOI:10.1038/s41598-022-10320-x (link is external)

mehr...(link is external)

Rothe K., Münster N., Hapfelmeier A., Ihbe-Heffinger A., Paepke S., Niemeyer M., Feihl S., Busch D.H., Kiechle M., Brambs C.E. 2022

Does the Duration of Perioperative Antibiotic Prophylaxis Influence the Incidence of Postoperative Surgical-Site Infections in Implant-Based Breast Reconstruction in Women with Breast Cancer? A Retrospective Study.

Plast Reconstr Surg. 2022 Apr 1;149(4):617e-628e. PMID: 35103626 DOI: 10.1097/PRS.0000000000008900 (link is external)

mehr...(link is external)

Schambeck S.E., Mateyka L.M., Burrell T., Graf N., Brill I., Stark T., Protzer U., Busch D.H., Gerhard M., Riehl H., Poppert H. 2022

Two-Year Follow-Up on Chemosensory Dysfunction and Adaptive Immune Response after Infection with SARS-CoV-2 in a Cohort of 44 Healthcare Workers

Life (Basel). 2022 Oct 7;12(10):1556. PMID: 36294991 PMCID: PMC9605261 DOI: 10.3390/life12101556 (link is external)

mehr...(link is external)

Sitali MC, Schmidt V, Mwenda R, Sikasunge CS, Mwape KE, Simuunza MC, Prazeres da Costa C, Winkler AS, Phiri IK.

Experimental animal models and their use in understanding cysticercosis: A systematic review.

PLoS One. 2022 Jul 19;17(7):e0271232. eCollection 2022. PMID: 35853079. DOI: 10.1371/journal.pone.0271232 (link is external)

mehr...(link is external)

Tsui C., Kretschmer L., Rapelius S. Gabriel, S.S., Chisanga D., Knöpper K., Utzschneider D.T., Nüssing S.,  Liao Y., Mason T., Valle Torres S., Wilcox S.A. ,Kanev K., Jarosch S., Leube J., Nutt S. L., Zehn D., Parish I.,  Kastenmüller W., Shi W., V. R. Buchholz, A. Kallies. 2022

MYB orchestrates T cell exhaustion and response to checkpoint inhibition.

Nature (2022). DOI: 10.1038/s41586-022-05105-1.(link is external)

mehr...(link is external)

Wagner K.I., Mateyka L.M., Jarosch S., Grass V., Weber S., Schober K., Hammel M., Burrell T., Kalali B., Poppert H., Beyer H., Schambeck S., Holdenrieder S., Strötges-Achatz A., Haselmann V., Neumaier M.I., Erber J., Priller A., Yazici S., Roggendorf H., Odendahl M., Tonn T., Dick A., Witter K., Mijočević H., Protzer U., Knolle P.A., Pichlmair A., Crowell C.S., Gerhard M., E. D'Ippolito, D.H. Busch. 2022

Recruitment of highly cytotoxic CD8 + T cell receptors in mild SARS-CoV-2 infection

Cell Rep., 2022 Jan 11;38(2):110214. is external)
mehr...(link is external)

Weber S., Kehl V., Erber J., Wagner K.I., Jetzlsperger A.M., Burrell T., Schober K., Schommers P., Augustin M., Crowell C.S., Gerhard M., Winter C., Moosmann A., Spinner C.D., Protzer U., Hoffmann D., E. D'Ippolito, D.H. Busch. 2022

CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patients.

PLoS One. 2022 May 25;17(5):e0268530. is external). eCollection 2022.

mehr...(link is external)

Xie K. , Fuchs H., Scifo E., Liu D., Aziz A., Aguilar-Pimentel  J.A., Amarie O.V.,  Becker L., da Silva-Buttkus P., Calzada-Wack J., Cho Y-L. , Deng Y., Edwards A.C., Garrett L., Georgopoulou C. , Gerlini R., Hölter S.M., Klein-Rodewald T., Kramer M. , Leuchtenberger S., Lountzi D., Mayer-Kuckuk P., Nover L.L., Oestereicher M.A., Overkott C., Pearson B.L., Rathkolb  B., Rozman J., Russ J. , Schaaf K., Spielmann N., Sanz-Moreno A. , Stoeger C., Treise I. , Bano D., Busch D.H., Graw J., Klingenspor M. , Klopstock T., Mock B.A.,  Salomoni P., Schmidt-Weber C., Weiergräber M., Wolf E., Wurst W., Gailus-Durner V., Breteler M.M.B., de Angelis M.H., Ehninger D. 2022

Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice

Nat Commun. 2022 Nov 11;13(1):6830. PMID: 36369285 PMCID: PMC9652467 DOI: 10.1038/s41467-022-34515-y(link is external)

mehr...(link is external)

Xue B., von Heyking K., Gassmann H. , Poorebrahim M. , Melanie Thiede  1 , Schober K. , Mautner J., Hauer J., Ruland  J., Busch  D.H.,  Thiel  U., Burdach  S.E.G. 2022

T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer

Cancers (Basel). 2022 Nov 8;14(22):5485. PMID: 36428578 PMCID: PMC9688113 DOI: 10.3390/cancers14225485(link is external)

mehr...(link is external)

Zöllkau J., Ankert J., Pletz M.W., Mishra S., Seliger G., Lobmaier S.M., Prazeres Da Costa C.U., Seidel V., Weizsäcker K.V., Jablonka A., Dopfer C., Baier M., Horvatits T., Reiter-Owona I., Groten T., Schleenvoigt B.T. 2022

Hepatitis E, Schistosomiasis and Echinococcosis-Prevalence in a Cohort of Pregnant Migrants in Germany and Their Influence on Fetal Growth Restriction.

Pathogens. 2022 Jan 3;11(1):58. PMID: 35056006 PMCID: PMC8780214 (link is external) DOI: 10.3390/pathogens11010058 (link is external)

mehr...(link is external)