Publikationen 2010

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain

Lückerath K, Kirkin V, Melzer IM, Thalheimer FB, Siele D, Milani W, Adler T, Aguilar-Pimentel A, Horsch M, Michel G, Beckers J, Busch DH, Ollert M, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Staal FJ, Rajalingam K, Hueber AO, Strobl LJ, Zimber-Strobl U, Zörnig M.

Blood. 2010

T regulatory cells in cord blood–FOXP3 demethylation as reliable quantitative marker

Liu J, Lluis A, Illi S, Layland L, Olek S, von Mutius E, Schaub B.

PLoS One. 2010 Oct 12; 5(10):e13267

Cytokine reporter mice in immunological research: perspectives and lessons learned.

Croxford AL, Buch T.

Imunology 2010,1365-2567

Toll-like receptor 3 mediates expression of clusterin/apolipoprotein J in vascular smooth muscle cells stimulated with RNA released from necrotic cells

M. Baiersdorfer, M. Schwarz, K. Seehafer, C. Lehmann, A. Heit, H. Wagner, C.J. Kirschning, C. Koch-Brandt

Exp Cell Res 316 (2010) 3489-3500

Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence

M. Yadav, J. Zhang, H. Fischer, W. Huang, N. Lutay, C. Cirl, J. Lum, T. Miethke, C. Svanborg

PLoS Pathog 6 (2010)

Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling

S. Wang, C. Schmaderer, E. Kiss, C. Schmidt, M. Bonrouhi, S. Porubsky, N. Gretz, L. Schaefer, C.J. Kirschning, Z.V. Popovic, H.J. Grone

Dis Model Mech 3 (2010) 92-103

Bone diseases: Interferon regulatory factor-8 suppresses osteoclastogenesis

H. Wagner

Nat Rev Rheumatol 6 (2010) 73-74

Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice

M. Rosemann, A. Ivashkevich, J. Favor, C. Dalke, S.M. Holter, L. Becker, I. Racz, I. Bolle, M. Klempt, B. Rathkolb, S. Kalaydjiev, T. Adler, A. Aguilar, W. Hans, M. Horsch, J. Rozman, J. Calzada-Wack, S. Kunder, B. Naton, V. Gailus-Durner, H. Fuchs, H. Schulz, J. Beckers, D.H. Busch, J.P. Burbach, M.P. Smidt, L. Quintanilla-Martinez, I. Esposito, T. Klopstock, M. Klingenspor, M. Ollert, E. Wolf, W. Wurst, A. Zimmer, M.H. de Angelis, M. Atkinson, U. Heinzmann, J. Graw

Mamm Genome 21 (2010) 13-27

Increased inflammation and impaired resistance to Chlamydophila pneumoniae infection in Dusp1(-/-) mice: critical role of IL-6

N. Rodriguez, H. Dietrich, I. Mossbrugger, G. Weintz, J. Scheller, M. Hammer, L. Quintanilla-Martinez, S. Rose-John, T. Miethke, R. Lang

J Leukoc Biol 88 (2010) 579-587

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

M. Ritter, O. Gross, S. Kays, J. Ruland, F. Nimmerjahn, S. Saijo, J. Tschopp, L.E. Layland, C. Prazeres da Costa

Proc Natl Acad Sci U S A 107 (2010) 20459-20464

Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes

P. Meyerhuber, H. Conrad, L. Starck, M. Leisegang, D.H. Busch, W. Uckert, H. Bernhard

J Mol Med (2010)

Epithelial Protein Lost in Neoplasm alpha (Eplin-alpha) is transcriptionally regulated by G-actin and MAL/MRTF coactivators

L. Leitner, D. Shaposhnikov, A. Descot, R. Hoffmann, G. Posern

Mol Cancer 9 (2010) 60

Core-specific adaptive regulatory T-cells in different outcomes of hepatitis C

B. Langhans, I. Braunschweiger, S. Arndt, W. Schulte, J. Satoguina, L.E. Layland, N. Vidovic, A. Hoerauf, J. Oldenburg, T. Sauerbruch, U. Spengler

Clin Sci (Lond) 119 (2010) 97-109

Generation of anti-TLR2 intrabody mediating inhibition of macrophage surface TLR2 expression and TLR2-driven cell activation

C.J. Kirschning, S. Dreher, B. Maass, S. Fichte, J. Schade, M. Koster, A. Noack, W. Lindenmaier, H. Wagner, T. Boldicke

BMC Biotechnol 10 (2010) 31

Prevalence and clinical aspects of human bocavirus infection in children

L. Karalar, J. Lindner, S. Schimanski, M. Kertai, H. Segerer, S. Modrow

Clin Microbiol Infect 16 (2010) 633-639

Comparison of gene expression profiles between human and mouse monocyte subsets

M.A. Ingersoll, R. Spanbroek, C. Lottaz, E.L. Gautier, M. Frankenberger, R. Hoffmann, R. Lang, M. Haniffa, M. Collin, F. Tacke, A.J. Habenicht, L. Ziegler-Heitbrock, G.J. Randolph

Blood 115 (2010) e10-19

Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance

M. Hinterberger, M. Aichinger, O.P. da Costa, D. Voehringer, R. Hoffmann, L. Klein

Nat Immunol 11 (2010) 512-519

Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer

W. Fischer, L. Windhager, S. Rohrer, M. Zeiller, A. Karnholz, R. Hoffmann, R. Zimmer, R. Haas

Nucleic Acids Res 38 (2010) 6089-6101

Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay

L. Dolken, G. Malterer, F. Erhard, S. Kothe, C.C. Friedel, G. Suffert, L. Marcinowski, N. Motsch, S. Barth, M. Beitzinger, D. Lieber, S.M. Bailer, R. Hoffmann, Z. Ruzsics, E. Kremmer, S. Pfeffer, R. Zimmer, U.H. Koszinowski, F. Grasser, G. Meister, J. Haas

Cell Host Microbe 7 (2010) 324-334

Microbial Toll/interleukin 1 receptor proteins: a new class of virulence factors

C. Cirl, T. Miethke

Int J Med Microbiol 300 (2010) 396-401

Ligand dimensions are important in controlling NK-cell responses

J. Brzostek, J.G. Chai, F. Gebhardt, D.H. Busch, R. Zhao, P.A. van der Merwe, K.G. Gould

Eur J Immunol 40 (2010) 2050-2059

Hemozoin: malaria’s “built-in” adjuvant and TLR9 agonist

Wagner, H.

Cell Host Microbe 2010. 7: 5-6

Chlamydophila pneumoniae downregulates MHC-class II expression by two cell type-specific mechanisms

Peschel, G., Kernschmidt, L., Cirl, C., Wantia, N., Ertl, T., Durr, S., Wagner, H., Miethke, T. and Rodriguez, N.

Mol Microbiol 2010

DCs in mouse models of intracellular bacterial infection

Neuenhahn, M., Schiemann, M. and Busch, D. H.

Methods Mol Biol 2010. 595: 319-329

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors

Moretti, A., Bellin, M., Jung, C. B., Thies, T. M., Takashima, Y., Bernshausen, A., Schiemann, M., Fischer, S., Moosmang, S., Smith, A. G., Lam, J. T. and Laugwitz, K. L.

FASEB J 2010. 24: 700-711

A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire

Liang, X., Weigand, L. U., Schuster, I. G., Eppinger, E., van der Griendt, J. C., Schub, A., Leisegang, M., Sommermeyer, D., Anderl, F., Han, Y., Ellwart, J., Moosmann, A., Busch, D. H., Uckert, W., Peschel, C. and Krackhardt, A. M.

J Immunol 2010. 184: 1617-1629

Pronounced phenotype in activated regulatory T cells during a chronic helminth infection

Layland, L. E., Mages, J., Loddenkemper, C., Hoerauf, A., Wagner, H., Lang, R. and da Costa, C. U.

J Immunol 2010. 184: 713-724

Immune requirements of post-exposure immunization with modified vaccinia Ankara of lethally infected mice

Lauterbach, H., Kassub, R., Patzold, J., Korner, J., Bruckel, M., Verschoor, A., Chaplin, P., Suter, M. and Hochrein, H.

PLoS ONE 2010. 5: e9659

T cell-dependence of Lassa fever pathogenesis

Flatz, L., Rieger, T., Merkler, D., Bergthaler, A., Regen, T., Schedensack, M., Bestmann, L., Verschoor, A., Kreutzfeldt, M., Bruck, W., Hanisch, U. K., Gunther, S. and Pinschewer, D. D.

PLoS Pathog 2010. 6: e1000836

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity

Flatz, L., Hegazy, A. N., Bergthaler, A., Verschoor, A., Claus, C., Fernandez, M., Gattinoni, L., Johnson, S., Kreppel, F., Kochanek, S., Broek, M., Radbruch, A., Levy, F., Lambert, P. H., Siegrist, C. A., Restifo, N. P., Lohning, M., Ochsenbein, A. F., Nabel, G. J. and Pinschewer, D. D.

Nat Med 2010. 16: 339-345

Requirements for control of B-cell lymphoma by NK cells

Brenner, C. D., King, S., Przewoznik, M., Wolters, I., Adam, C., Bornkamm, G. W., Busch, D. H., Rocken, M. and Mocikat, R.

Eur J Immunol 2010. 40: 494-504

Specific CD8 T cells in IgE-mediated allergy correlate with allergen dose and allergic phenotype

Aguilar-Pimentel, J. A., Alessandrini, F., Huster, K. M., Jakob, T., Schulz, H., Behrendt, H., Ring, J., de Angelis, M. H., Busch, D. H., Mempel, M. and Ollert, M.

Am J Respir Crit Care Med 2010. 181: 7-16