Publications of the year 2021

Anisuzzaman, S. Frahm, U.F. Prodjinotho, S. Bhattacharjee, A. Verschoor, and C. Prazeres da Costa. 2021.

Host-Specific Serum Factors Control the Development and Survival of Schistosoma mansoni.

Front. Immunol., is external)

more...(link is external)

Berni, F., E. Kalfopoulou, A.M. Gimeno Cardells, F. Carboni, D. van der Es, F. Romero-Saavedra, D. Laverde, K. Miklic, S. Malic, T.L. Rovis, S. Jonjic, S. Ali, H.S. Overkleeft, C.H. Hokke, A. van Diepen, R. Adamo, J. Jiménez-Barbero, G.A. van der Marel, J. Huebner, and J.D.C. Codée. 2021.

Epitope Recognition of a Monoclonal Antibody Raised against a Synthetic Glycerol Phosphate Based Teichoic Acid.

ACS Chem Biol. is external)

more...(link is external)

Deschler, S., J. Kager, J. Erber, L. Fricke, P. Koyumdzhieva, A. Georgieva, T. Lahmer, J.R. Wiessner, F. Voit, J. Schneider, J. Horstmann, R. Iakoubov, M. Treiber, C. Winter, J. Ruland, D.H. Busch, P.A. Knolle, U. Protzer, C.D. Spinner, R.M. Schmid, M. Quante, and K. Bottcher. 2021.

Mucosal-Associated Invariant T (MAIT) Cells Are Highly Activated and Functionally Impaired in COVID-19 Patients.

more...(link is external)

Fischer D.S., Ansari M., Wagner K.I., Jarosch  S., Huang  Y., Mayr  C.H., Strunz  M., Lang  N.J., D'Ippolito  E., Hammel  M., Mateyka  L.M., Weber  S., Wolff  L.S., Witter  K. , Fernandez  I.E., Leuschner  G., Milger  K., Frankenberger  M. , Nowak  L., Heinig-Menhard  K., Koch  I., Stoleriu  M.G., Hilgendorff  A. , Behr  J. , Pichlmair  A., Schubert  B., Theis  F.J., Busch  D.H., Schiller H.B., Schober  K. 2021

Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'

Nat Commun. 2021 Jul 26;12(1):4515. PMID: 34312385 PMCID: PMC8313584 (link is external)DOI: 10.1038/s41467-021-24730-4 (link is external)

more…(link is external)

Habib M, Esen M, Honkpehedji J, Klug SJ, Lobmaier S, Vogg K, Bustinduy AL, Ullrich A, Reinhard-Rupp J, Akim Adegnika A, Prazeres da Costa C. 2021

The Challenges in Women’s Health in sub-Saharan Africa: Lessons learned from an integrative multistakeholder workshop in Gabon.

J Glob Health 2021 Sep 4;11:02002. doi: 10.7189/jogh.11.02002(link is external). eCollection 2021.

Habib M, Lange U, Ludwig S, Prazeres da Costa C. 2021

The Impact of the COVID-19 Pandemic on Pregnancy, Birth and Sexual & Reproductive Health and Rights – Perspectives from Germany and Somalia.

J Glob Health 2021 Sep 4;11:03085. doi: 10.7189/jogh.11.03085(link is external). eCollection 2021.

Heim, M., T. Lahmer, S. Rasch, S. Kriescher, W. Berg-Johnson, K. Fuest, B. Kapfer, G. Schneider, C.D. Spinner, F. Geisler, J.R. Wiessner, K. Rothe, S. Feihl, and A. Ranft. 2021.

Rapid clinical evolution for COVID-19 translates into early hospital admission and unfavourable outcome: a preliminary report.

Multidiscip Respir Med. 16:744. is external)

more...(link is external)

Jarosch S., Köhlen J, Sarker R.S.J. , Steiger K. , Janssen K.P. ,Christians A. , Hennig C. , Holler  E., E. D'Ippolito, D.H. Busch. 2021

Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometry.

Cell Rep Methods., 2021 Oct 27;1(7):100104. is external)

more...(link is external)

Kalin, R.E., L. Cai, Y. Li, D. Zhao, H. Zhang, J. Cheng, W. Zhang, Y. Wu, K. Eisenhut, P. Janssen, L. Schmitt, W. Enard, F. Michels, C. Fluh, M. Hou, S.V. Kirchleitner, S. Siller, M. Schiemann, I. Andra, E. Montanez, C. Giachino, V. Taylor, M. Synowitz, J.C. Tonn, L. von Baumgarten, C. Schulz, I. Hellmann, and R. Glass. 2021.

TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression.

Cell Syst. 12:248-262 e247. is external)

more...(link is external)

Kretschmer, L., D.H. Busch, and V.R. Buchholz. 2021.

A Single-Cell Perspective on Memory T-Cell Differentiation.

Cold Spring Harb Perspect Biol.

more...(link is external)

Lacorcia, M., S. Bhattacharjee, K. Laubhahn, F. Alhamdan, M. Ram, A. Muschaweckh, D.P. Potaczek, A. Kosinska, H. Garn, U. Protzer, H. Renz, and C. Prazeres da Costa. 2021.

Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function.

The Journal of allergy and clinical immunology. is external)

more...(link is external)

Lahmer, T., S. Kriescher, A. Herner, K. Rothe, C.D. Spinner, J. Schneider, U. Mayer, M. Neuenhahn, D. Hoffmann, F. Geisler, M. Heim, G. Schneider, R.M. Schmid, W. Huber, and S. Rasch. 2021.

Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: Results from the prospective AspCOVID-19 study.

PLoS One. is external)

more...(link is external)

Mathewson, N.D., O. Ashenberg, I. Tirosh, S. Gritsch, E.M. Perez, S. Marx, L. Jerby-Arnon, R. Chanoch-Myers, T. Hara, A.R. Richman, Y. Ito, J. Pyrdol, M. Friedrich, K. Schumann, M.J. Poitras, P.C. Gokhale, L.N. Gonzalez Castro, M.E. Shore, C.M. Hebert, B. Shaw, H.L. Cahill, M. Drummond, W. Zhang, O. Olawoyin, H. Wakimoto, O. Rozenblatt-Rosen, P.K. Brastianos, X.S. Liu, P.S. Jones, D.P. Cahill, M.P. Frosch, D.N. Louis, G.J. Freeman,  K.L. Ligon, A. Marson, E.A. Chiocca, D.A. Reardon, A. Regev, M.L. Suva, and K.W. Wucherpfennig. 2021.

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.

Cell. 184:1281-1298 e1226. is external)

more...(link is external)

Mejías-Luque, R. 2021.

Senescence: A Novel Driver of Helicobacter pylori-Induced
Gastric Atrophy.

Cell Mol Gastroenterol Hepatol. 11:887-888. is external)

more...(link is external)

Mitsdörffer, M., G. Di Liberto, S. Dötsch, C. Sie, I. Wagner, M. Pfaller, M. Kreutzfeldt, S. Fräßle, L. Aly, B. Knier, D.H. Busch, D. Merkler, and T. Korn. 2021.

Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity.

Brain, awab235, (link is external) is external)

more...(link is external)

Müller  T.R. , Jarosch  S. , Hammel  M. , Leube  J. , Grassmann  S. , Bernard  B. , Effenberger  M. , Andrä  I. , Zeeshan Chaudhry  M. , Käuferle  T. , Malo  A. , Cicin-Sain  L. , Steinberger  P. , Feuchtinger  T.  , Protzer  U. , Schumann  K. , Neuenhahn  M. , Schober  K. , Busch  D.H. 2021

Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy

Cell Rep Med. 2021 Aug 17;2(8):100374. PMID: 34467251, PMCID: PMC8385324 (link is external), DOI: 10.1016/j.xcrm.2021.100374 (link is external)

more...(link is external)

Neumeyer, V., A. Brutau-Abia, M. Allgäuer, N. Pfarr, W. Weichert, C. Falkeis-Veits, E. Kremmer, M. Vieth, M. Gerhard, and R. Mejías-Luque. 2021.

Loss of RNF43 Function Contributes to Gastric Carcinogenesis by Impairing DNA Damage Response.

Cell Mol Gastroenterol Hepatol. 11:1071-1094. is external)

more...(link is external)

Rothe, K., S. Feihl, J. Schneider, F. Wallnofer, M. Wurst, M. Lukas, M. Treiber, T. Lahmer, M. Heim, M. Dommasch, B. Waschulzik, A. Zink, C. Querbach, D.H. Busch, R.M. Schmid, G. Schneider, and C.D. Spinner. 2021.

Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship.

Eur J Clin Microbiol Infect Dis. 40pages 859–869


Rothe, K., S. Rasch, N. Wantia, A. Poszler, J. Ulrich, C. Schlag, W. Huber, R.M. Schmid, D.H. Busch, and T. Lahmer. 2021.

Aspergillus fumigatus cholangitis in a patient with cholangiocarcinoma: case report and review of the literature.

Infection. 49, 159–164


Sasse, D., C.D. Spinner, K. Rothe, J. Schneider, J. Gaa, and S. Wurstle. 2021.

Treatment of intestinal tuberculosis with small bowel perforation: a case report.

J Med Case Rep. 15:144.

more...(link is external)

Schambeck  S.E., Crowell  C.S.,  Wagner  K.I., D'Ippolito  E., Burrell  T., Mijočević  H. , Protzer  U., Busch  D.H., Gerhard  M., Poppert  H., Beyer  H. 2021

Phantosmia, Parosmia, and Dysgeusia Are Prolonged and Late-Onset Symptoms of COVID-19

J Clin Med. 2021 Nov 12;10(22):5266. PMID: 34830550 PMCID: PMC8618742 (link is external) DOI: 10.3390/jcm10225266 (link is external)

more...(link is external)

Schneider, J., H. Mijocevic, K. Ulm, B. Ulm, S. Weidlich, S. Wurstle, K. Rothe, M. Treiber, R. Iakoubov, U. Mayr, T. Lahmer, S. Rasch, A. Herner, E. Burian, F. Lohofer, R. Braren, M.R. Makowski, R.M. Schmid, U. Protzer, C. Spinner, and F. Geisler. 2021.

SARS-CoV-2 serology increases diagnostic accuracy in CT-suspected, PCR-negative COVID-19 patients during pandemic.

Respir Res. 22:119.

more...(link is external)

Silvestre-Roig, C., P. Lemnitzer, J. Gall, S. Schwager, A. Toska, L. Yvan-Charvet, M. Detmar, and O. Soehnlein. 2021.

Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions.

Circ Res. 128:284-286. is external)

more...(link is external)

Stief, T.A., T. Kaeuferle, T.R. Müller, M. Doring, L.M. Jablonowski, K. Schober, J. Feucht, K.M. Dennehy, S. Willier, F. Blaeschke, R. Handgretinger, P. Lang, D.H. Busch,
and T. Feuchtinger. 2021.

Protective T-cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections.

Mol Ther. is external)

more...(link is external)

Vejzagic, N., U.F. Prodjinotho, N. El-Khafif, R. Huang, A. Simeonov, T. Spangenberg, and C. Prazeres da Costa. 2021.

Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.

PLoS Negl Trop Dis. is external)

more...(link is external)

Wagner, L.F., I. Lanzl, K. Rothe, J. Schneider, A. Zink, D. Zapp, C. Schwerdtfeger, M. Lee, S. Weidlich, M. Neuenhahn, D. Loos, and C.D. Spinner. 2021.

Clinical and Ophthalmological Characteristics of Ocular Syphilis in a Retrospective Tertiary Hospital Cohort.

Sex Transm Dis. 48:436-442. doi: 10.1097/OLQ.0000000000001329

more...(link is external)

Weickert, M.T., J.S. Hecker, M.C. Buck, C. Schreck, J. Riviere, M. Schiemann, K. Schallmoser, F. Bassermann, D. Strunk, R.A.J. Oostendorp, and K.S. Gotze. 2021.

Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression.

Sci Rep. 11:5944. DOI: 10.1038/s41598-021-85122-8 (link is external)

more...(link is external)

Wiedemann, G.M., J. Schneider, M. Verbeek, B. Konukiewitz, C.D. Spinner, H. Einwachter, R.M. Schmid, and K. Rothe. 2021.

An Eschar-like souvenir from a journey to Colombia: Ecthyma gangrenosum as a differential diagnosis of tropical diseases in immunocompromised patients - a case report.

BMC Infect Dis. 21:344.

more...(link is external)