Selected Publications


Höfer, T., Barile, M., Flossdorf, M. (2016). Stem-cell dynamics and lineage topology from in vivo fate mapping in the hematopoietic system. Current Opinion in Biotechnology 39, 150–156.

Schmid, B., Rinas, M., Ruggieri, A., Accosta, E.G., Bartenschlager, M., Reuter, A., Fischl, W., Harder, N., Bergeest, J.-P., Flossdorf, M., Rohr, K., Höfer, T., Bartenschlager, R. (2015). Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2’-O-Methylation Mutant. PLoS Pathogens 11, e1005345.

Flossdorf, M., Rössler, J., Buchholz, V.R., Busch, D.H., Höfer, T. (2015). CD8+ T cell diversification by asymmetric cell division. Nature Immunology 16, 891–893. 

Busch, K., Klapproth, K. *, Barile, M. *, Flossdorf, M.*, Holland-Letz, T., Schlenner, S.M., Reth, M., Höfer, T., Rodewald, H.-R. (2015). Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature 518, 542–546.

(*shared second author)

Helmstetter, C.*, Flossdorf, M.*, Peine, M., Kupz, A., Zhu, J., Hegazy, A.N., Duque-Correa, M.A., Zhang, Q., Vainshtein, Y., Radbruch, A., Kaufmann, S.H., Paul, W.E., Höfer, T., Löhning, M. (2015). Individual T helper cells have a quantitative cytokine memory. Immunity 42, 108–122.

(*shared first author)

Graef, P., Buchholz, V.R., Stemberger, C., Flossdorf, M., Henkel, L., Schiemann, M., Drexler, I., Höfer, T., Riddell, S.R., Busch, D.H. (2014). Serial transfer of single cell-derived immunocompetence reveals stemness of CD8+ central memory T cells. Immunity 41, 115–126.

Buchholz, V.R.*, Flossdorf, M.*, Hensel, I., Kretschmer, L., Weissbrich, B., Gräf, P., Schiemann, M., Höfer, T., Busch, D.H. (2013). Disparate individual fates compose robust CD8+ T cell immunity. Science 340, 630–635.

(*shared first author)

Rand, U., Rinas, M., Schwerk, J., Nöhren, G., Linnes, M., Kröger, A., Flossdorf, M., Kály-Kullai, K., Hauser, H., Höfer, T., Köster, M. (2012). Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response. Molecular Systems Biology 8, 584.

Stittrich, A.-B., Haftmann, C., Sgouroudis, E., Kühl, A.A., Hegazy, A.N., Panse, I., Riedel, R., Flossdorf, M., Dong, J., Fuhrmann, F., et al. (2010). The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. Nature Immunology 11, 1057–1062.

Busse, D., de la Rosa, M., Hobiger, K., Thurley, K., Flossdorf, M., Scheffold, A., Höfer, T. (2010). Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proceedings of the National Academy of Sciences 107, 3058–3063.

Braam, F.*, Flossdorf, M.*, Chivukula, R.S., Di Chiara, S., Simmons, E.H. (2008). Hypercharge-universal topcolor. Physical Review D 77, 055005.

(*shared first author)